Dual Pathogenesis of Primary and Recurrent Pterygium: Immunohistochemical Proof

Introduction: Pterygium is a common ophthalmic problem in the Middle East where exposures to dust and sun rays are risk factors. The condition more prevalent middle-aged males can be considered as an aging process. aim of this study test both degenerative proliferative components by reduced glutathione topoisomerase one activity. Methods: applied immunohistochemistry staining for 1. Results: samples expressed positive most primary conditions all secondary Pterygium. On other hand, 1 focal activity suggesting progenitor cell role pathogenesis conjunction with oxidative stress. Conclusion: represents dual pathology component that needs further studies. It possible use combination markers predict prognosis behavior.